IUI vs IVF Success Rates

IUI vs IVF Success Rates
Table of Contents

In life, when we face choices, we often get confused. And also, our mind naturally analyses the factors to weigh which one is best. There is no exception, even in fertility treatment, where numerous advanced techniques are available. Thus, individuals seeking fertility treatment will choose the best option based on their unique health needs and personal situation. This article compares the success rates of IUI and IVF to guide your decision. Keep reading.

Understanding IUI and IVF

Before comparing success rates, it is important to understand the difference between IUI and IVF:

IUI (Intrauterine Insemination)

A procedure where sperm is directly placed into the uterus and this treatment is ideal for:
– Mild male factor infertility
– Unexplained infertility
– Couples of same gender
– Women with infertility concerns or uterine condition or cervical issues

IVF (In Vitro Fertilisation)

A laboratory procedure combining eggs and sperm outside the body, resulting in fertilised egg which is then placed in the uterus and it is recommended for candidates with 

– Blocked fallopian tubes
– Severe male factor infertility
– Previous IUI failure
– Women with PCOS or repeated miscarriages or advanced maternal age (35+ years)

Usually, couples start with IUI and move to IVF if they don’t get any positive outcome due to IUI failure. However, in some cases, IVF treatment may be recommended directly, depending on individual circumstances.

Success Rate Factors

Before understanding the IUI and IVF success rates data, you should know what are all the conditions that determine the success.

Age

  • –      Women under 35: Higher chances of success
  • –      Women 35-37: Gradual decline in success rates
  • –      Women 38-40: Significant decline in success rates
  • –      Women over 40: Lower chances of success

Egg/Sperm Quality

  • –      Healthy eggs and sperm: Better success rates
  • –      Poor egg/sperm quality: Reduced success rates

Medical Conditions

  • –      PCOS will disturb the natural ovulation
  • –      Uterine tissue growth causing pain and infertility
  • –      Thyroid related hormonal imbalance can affect fertility

Previous Fertility Treatments

  • –      Previous successful treatments will increase the confidence
  • –      Previous unsuccessful treatments can lower success rates

Lifestyle Factors

  • –      Smoking: Reduces fertility and success rates
  • –      Weight (obesity/underweight): Affects hormone regulation and fertility
  • –      Stress and poor diet can affect overall fertility

IUI Success Rates

It is not possible to generalise the success rate because it varies from person to person and also different clinic procedures. However, average data is available.

Average Success Rates

Though IUI is a procedure with a minimum number of steps, it should meet all the demands to give possible outcomes. The treatment’s success could be assessed based on the age factor. 

Women within the 28 to 35-year-old age group have a higher possibility as opposed to women who are older than 35 years. This is mainly because egg quality and follicle development will have reduced chances of ovulation at later ages. 

Additionally, the quality of sperm is considered for getting positive results in IUI. The process should be completed within an accommodated time frame. Delaying any steps will greatly impact IUI success. 

Other health issues unrelated to fertility, and medications taken for those conditions, may reduce the effectiveness of IUI medications.

Number of Attempts Required

Usually, fertility centres suggest 3-4 attempts before considering alternative options like IVF.

IVF Success Rates

IVF treatment is considered more effective than IUI, but you should analyse the factors before starting the procedure.

Average Success Rates

IVF success rate vary from person to person, mainly concerning age factors. Thus, success rates for women under 35 is 40-50% per cycle, 30-40% for women between 35-37 years, 20-30% success rate within 38-40 years, and the least chance with a success rate of 10-20% for women above 40. 

This reason is due to the quality and quantity of eggs that are more abundant in younger women. The increase in age lowers down both the egg quality and quantity thus reducing success rates. The conditions like PCOS need to be managed by diet and medications because PCOS is a condition involving ovulation.

 Also, the success rates are caused by experience and technology used at the fertility clinic and specific IVF policies.

Number of Attempts Required

Couples are usually advised to undergo 2-3 IVF attempts before reassessing the treatment. The cumulative pregnancy rates increase with the number of attempts. 

However, factors like cost, emotional preparedness, and personal circumstances often influence the decision to continue or discontinue IVF attempts.

Comparison of IUI and IVF Success Rates

  1.   The following table compares the average success rates of IUI and IVF based on age group.
Age Group IUI Success Rate (%) IVF Success Rate (%)
≤34
10-20
47-57
35-37
8-15
37-47
38-40
5-12
23-27
41-42
4-8
13-23
43-44
2-5
5-13
≥45
<2
<5

 This table shows you clearly how the chance of success decreases with increasing age.

  1.   When the number of fertility treatment cycles increases, the chances of success also increase. The following table shows the cumulative success rates of IUI and IVF treatments based on the number of cycles.
Cycles IUI Cumulative Success Rate (%) IVF Cumulative Success Rate (%)
1
15-20
40-50
2
25-35
60-70
3
35-45
75-85
4
45-55
85-95

 This data clearly shows that success rates for IUI and IVF increase with each cycle, but IUI increases at a slower pace, whereas IVF increases more rapidly.

3.   Success rate for IUI and IVF: fresh(fresh embryos) vs frozen cycles (frozen embryos).

Cycle Type IUI Success Rate (%) IVF Success Rate (%)
Fresh Cycle
15-20
40-50
Frozen Cycle
10-15
45-55

Frozen IVF cycles have a slightly higher success rate than fresh cycles, whereas in IUI, fresh cycles have a higher success rate compared to frozen. The reason is that in IVF, frozen embryos enhance the quality and ensure optimal uterine operation. But in the case of sperm, fresh is more viable than frozen in the IUI process.

  1.   The real success of fertility treatments, whether IUI or IVF, is achieving a live birth. Let’s see the success rates of IUI and IVF based on live births.
Treatment Live Birth Rate %
IUI
10-20
IVF
30-50

To be noted that it is not the individual percentage rate. It is based on the number of women who underwent this treatment and, out of them, how many women gave birth.

Conclusion

If you have doubts regarding the success rates, it will be cleared when you analyse the above data. From the success rates data given on different scales, you can understand under which category you fall.

Moreover, ensuring financial resources and emotional support can ensure the complete process without breaks or delays. It is clearly evident from the available data that IVF has higher success rates compared to IUI. It is necessary to choose the right treatment option and undergo the treatment process with patience and persistence to achieve a dream of creating a family.

FAQs

Age, egg/sperm quality, health conditions, and lifestyle factors impact IUI and IVF success. Understanding these factors helps couples choose the best treatment option.

IVF generally has higher success rates when compared to IUI, especially for women below 35 years.

Couples are usually advised to undergo 2-3 attempts if it is IVF attempts and 3-4 attempts in IUI before reconsidering treatment. Success rates increase with multiple attempts, but factors like cost and emotional preparedness also play a role.

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Dr. Rukkayal Fathima

Dr Rukkayal Fathima, India's Leading Gynaecologist and the best fertility doctor in Chennai. She has 11+ years of experience and treated 1000+ patients. She finished her M. S., Obstetrics and Gynaecology from the Institute of Obstetrics & Gynaecology (Madras Medical College), Chennai. She is a visiting consultant at St. Isabelle Hospital, Motherhood Hospital, Rainbow Hospital & Mehta Hospital. Dr Rukkayal Fathima specialises in Obstetrics care, Early Pregnancy Scan, IVF, ICSI, TESA/Micro TESE, Menopause advice, Gynaecological surgeries and endoscopy. She is a Co-Founder of Hive Fertility, the Best Fertility Center in Chennai.

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